Tone.js is an extensive Web Audio framework to create interactive music. It offers features like transport and timing, prebuilt synths/effects and DSP modules to build your own synthesizers, effects, and complex control signals.
Flocking is an audio synthesis framework to build creative and experimental sound projects. Its goal is to promote a community-minded approach to instrument design and composition. In Flocking, unit generators and synths are specified as JSON, making it easy to save and share your synthesis algorithms.
This Node.js module abstracts the command-line usage of SoX so you can create complex SoX commands and run them with ease. For example, you will be able to play concatenate and trim audio files, transcode audio streams, apply a wide variety of effects, etc.