The WebMidi JavaScript library will help you tame the lower-lever HTML5 Web MIDI API. It will let you send and receive MIDI messages with ease, control instruments with user-friendly functions (playNote, sendPitchBend, etc.) and react to MIDI input with simple event listeners (noteon, pitchbend, controlchange, etc.).
The osc.js library implements the Open Sound Control protocol. It lets you read and write OSC-formatted binary message via plain JavaScript objects. It can receive OSC data in different ways: serial port APIs such as node-serialport or chrome.serial, socket APIs such as Node.js dgram or WebRTC data channels, WebSockets or binary XHR messages should all work.
The node-midi library is a wrapper for the RtMidi C++ library. It provides realtime MIDI I/O on Linux (ALSA & Jack), Macintosh OS X (CoreMidi) and Windows (Multimedia).
Tuio.js is a JavaScript implementation of the TUIO library for multitouch and tangible interaction in the web browser. It brings a 1:1 port of the original TUIO Java library. Tuio.js uses Node.js and Websockets (Socket.IO) to push OSC/TUIO messages to the browser.
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